Description
AHK-Cu is a copper-binding tripeptide (alanyl-L-histidyl-L-lysine) closely related to GHK-Cu, differing at the first residue. It is studied in dermatological and hair-follicle research for effects on dermal papilla cells, angiogenic signalling and extracellular-matrix synthesis.
10 vials per box. Strengths are per vial; prices are per box.
Research summaries
AHK-Cu and dermal papilla cell activity
In vitro work on copper tripeptides reports that AHK-Cu increased proliferation of cultured human dermal papilla cells and raised expression of VEGF and other growth factors associated with the anagen phase of the follicular cycle. Effects were copper-dependent and not reproduced by the uncomplexed peptide.
Most AHK-Cu research is cell-culture work on hair-follicle biology. The copper complex, not the bare peptide, appears to drive the reported activity.
Copper peptides in matrix remodeling
Comparative studies of copper-binding tripeptides describe stimulation of collagen and elastin synthesis in fibroblast models, with copper acting as a cofactor for lysyl oxidase. AHK-Cu is generally reported as less extensively characterized than GHK-Cu across these endpoints.
AHK-Cu sits in the same family as GHK-Cu but has a much smaller published literature behind it.
For research use only. Not for human or veterinary use.
